Department of Electrical and Computer Engineering, College of Engineering, University of Tehran, Tehran, Iran
Graphene, after its first production in 2004 have received lots of attentions from researchers because of its unique properties. High mobility, high sensitivity, high selectivity and high surface area make graphene excellent choice for bio application. One of promising graphene base device that has amazingly high sensitivity is graphene field-effect transistor (GFET). This review selectively summarizes the recent progress in fabrication and application of GFET for various biosensors. This article begins with short description and history of ion-sensitive field-effect transistor (ISFET). After that, advantages of graphene ISFET will be summarized. Then, GFET fabrication process including graphene sheet growth different methods, drain/source electrode deposition and lithography and passivation will be discussed. Finally, different application of GFET in detection of Deoxyribonucleic acid (DNA), pH and protein will be present and quality of GFET biosensor will be examined.