Synergistic Effects of Taxus baccata Extract Mixtures with Silver Nanoparticles against Bacteria and Fungal

Document Type : Research Paper


1 Department of Chemistry, Yasouj University, Yasouj , Iran

2 Department of Biology, Yasouj University, Yasouj , Iran

3 Department of Chemistry, Yasuj University, Yasouj, Iran


Plants are rich source of natural products used for centuries to cure various the plant-derived medicines are based upon the premise that they contain natural substances that can promote health and alleviate illness. Silver NPs represent material, which can be used as a potential antibacterial agent in medical applications and different commercial products due to its biological activity. Recently, silver NPs as well as various silver-based compounds containing ionic silver (Ag+), exhibiting high antimicrobial activity, have been synthesized. Due to its biological activity. This study aimed to determine the effect of silver nanoparticles combined with Taxus baccata L. In this study the use with Hydroalcohlic extract Taxus baccata L. of method maceration (soaking) was prepared. Also antibacterial/antifungal activities of Compounds (extract, AgNPs, mixture of extract with AgNPs) were tested against three Gram-negative bacteria Escherichia coli (ATCC33218), Acinetobacter baumannii (ATCC150504) and Klebsiella pneumoniae (ATCC1827)  and Gram-positive bacteria Staphylococcus aureus (ATCC 25293) and also fungi Aspergillus oryzae (ATCC20423). This research combines the inherent antimicrobial activity of silver metals with the Taxus baccata extract, yielding antibacterial activity-enhanced AgNPs.