A novel method of cinnamon oil nanocapsulation in core-shell chitosan-alginate by freeze dryer

Document Type: Research Paper

Abstract

The objective of this work was to characterize the cinnamon oil nanocapsule that contained alginate-chitosan as coating agents. In this work, cinamonn oil loaded chitosan nanoparticles (CS-alginate NP-cinamonn) are prepared by a two-step process including oil/water emulsion and ionic gelation. In this study, cinamon as a core material was nanoencapsulated with chitosan alginate at a ratio of 1:4 (core: wall). Fourier transform–infrared analysis revealed potential interactions among the constituents in the composite NPs. Scanning electron microscopic analysis showed that the particles were nearly spherical in shape with an average size of 100±20 nm. Encapsulation efficiency (%) of cinamonn in composite NPs showed considerable increase over ALG-CS NPs with tween 80. Results showed that emulation drop let size by this method were 40.2 ± 2.4 nm. TEM, it was indicated that particles size varies from the range of 50nm.

Keywords