Document Type: Review Paper
Nano-Hydroxyapatite (nHAP) is a very valuable mineral that is widely used in tissue
engineering as well as bone and dental repair. Moreover, it is a major component of bone, enamel and dentin that can interact effectively with healing tissues due to its high biocompatibility. It is important to note that the purpose of its medical application can be identified based on the structure and synthesis of HAP. This study aimed to efficiently review all the previously conducted studies on synthesis and application of nHAP over the years of researchers' efforts and present the results for optimizing biocompatible material synthesis.